Uncertainty-Aware Real-Time Decision-Making in Digital Twins

Digital Twin research not only focuses on creating virtual replicas of physical systems, but also on enabling bi-directional interaction between the physical and the virtual counterpart. By integrating data from sensors, IoT devices, and advanced analytics, Digital Twins provide a dynamic, data-driven approach to understanding and optimizing complex systems.

This stream of research leverages Digital Twin technology for system design, performance optimization, and lifecycle management, with an emphasis on enhancing decision-making and predictive capabilities. Through the integration of AI, machine learning, uncertainty quantification, and real-time data, I aim to develop solutions that bridge the gap between physical and digital domains — positioning Digital Twins as trustworthy and intelligent learning systems that offer robust, real-time decision support.

Selected journal articles

An Attention-Based Spatio-Temporal Neural Operator for Evolving Physics

Karkaria, V., Lee, D., Chen, Y.-P., Yu, Y., & Chen, W.
IOP Machine Learning: Science and Technology 6 (2025): 045036

Uncertainty-Aware Digital Twins: Robust Model Predictive Control Using Time-Series Deep Quantile Learning

Chen, Y.-P., Tsai, Y.-K., Karkaria, V., & Chen, W.
ASME Journal of Mechanical Design, Special Issue: Data-Driven Design under Uncertainty, 148(2): 021702

Real-Time Decision-Making for Digital Twin in Additive Manufacturing with Model Predictive Control using Time-Series Deep Neural Networks

Chen, Y.-P., Karkaria, V., Tsai, Y.-K., Rolark, F., Quispe, D., Gao, R. X., Cao, J., & Chen, W.
Journal of Manufacturing Systems 80 (2025): 412–424
🏆 NAMRC 53 Outstanding Paper Award

An Optimization-Centric Review on Integrating Artificial Intelligence and Digital Twin Technologies in Manufacturing

Karkaria, V., Tsai, Y.-K., Chen, Y.-P., & Chen, W.
Engineering Optimization (2025) 1–47

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